Trying to heal stroke damage with stem cells

Stroke is the leading cause of permanent disability in the U.S., striking nearly 800,000 people each year. Hemorrhagic, or bleeding, stroke is particularly devastating says Mayo Clinic neurologist and critical care expert Dr. William D. Freeman. “About 40 percent of hemorrhagic stroke patients die within a month, and half of the survivors have some type of impairment,” he adds.

source

Corneal Suturing, Part 1- A Curriculum for Suturing the Cornea

Leo J. Maguire, M.D., consultant in cornea and external disease, developed the curriculum in resident corneal surgery at Mayo Clinic. In this series of videos, he discusses how to engineer the placement of a suture in a corneal transplant so that the length, depth, and radiality of the sutures are consistent around the circumference of a corneal graft. Mayo has used this methodology successfully with its Ophthalmology residents for the past 15 years.

source

New drug for MS is milestone for patients and research

A new drug, Ocrevus (ocrelizumab), has been approved by the U.S. Food and Drug Administration (FDA) to treat multiple sclerosis (MS). The National Multiple Sclerosis Society says it’s a “game changer” and Mayo Clinic neurologist Dr. Dean Wingerchuk says, “The approval of ocrelizumab is an important milestone both for people with MS and MS research.”

In a news statement released Wed. March 29, Dr. Billy Dunn, director of the Division of Neurology Products in the FDA’s Center for Drug Evaluation and Research says, “This therapy not only provides another treatment option for those with relapsing MS, but for the first time provides an approved therapy for those with primary progressive MS.”

More health and medical news on the Mayo Clinic News Network http://newsnetwork.mayoclinic.org/

source

Type B Thoracic Aortic Dissection: When to Intervene

In this roundtable discussion originally posted on Medscape Cardiology, Mayo Clinic Cardiology, Cardiac Surgery, and Vascular Surgery specialists Robert D. McBane, M.D., Randall R. De Martino M.D., Thomas C. Bower, M.D., and Alberto Pochettino, M.D., discuss when to intervene in Type B thoracic aortic dissection cases.

source

Differentiating Childhood Apraxia of Speech (CAS) from other types of speech sound disorders

Dr. Edythe Strand, Emeritus Professor and Consultant, division of Speech Pathology, Department of Neurology, Mayo Clinic, compares and contrasts CAS with other types of speech disorders, including phonological impairment and dysarthria.

For more information, visit http://mayocl.in/2ifnYX3

source

Corneal Suturing, Part 5 – Suturing the Wound

Leo J. Maguire, M.D., consultant in cornea and external disease, developed the curriculum in resident corneal surgery at Mayo Clinic. In this series of videos, he discusses how to engineer the placement of a suture in a corneal transplant so that the length, depth, and radiality of the sutures are consistent around the circumference of a corneal graft. Mayo has used this methodology successfully with its Ophthalmology residents for the past 15 years.

source

MR Fusion Biopsy at Mayo Clinic

MR fusion-guided biopsy of the prostate is a state of the art technique for the early diagnosis of prostate cancer. It allows for diagnosis of difficult to reach cancers with conventional biopsy techniques. Uses the most advanced technology to image the prostate with MRI.

Learn more about this new technique with Mayo Clinic urologist Julio Gundian.

More information at www.mayoclinic.org

source

What Are the Signs and Symptoms of Ovarian Cancer?

Each year, the first Friday in September is designated as Wear Teal Day.  On this day, organizations unite in an effort to encourage you to dress in teal and educate yourself and those around you about the symptoms and risk factors of Ovarian Cancer.

What is Ovarian Cancer?

Ovarian cancer is a disease in which, depending on the type and stage, malignant (cancerous) cells are found inside, near, or on the outer layer of the ovaries. An ovary is one of two small, almond-shaped organs located on each side of the uterus that store eggs, or germ cells, and produce female hormones estrogen and progesterone.

Cancer Basics

Cancer develops when abnormal cells in a part of the body (in this case, the ovary) begin to grow uncontrollably. This abnormal cell growth is common among all cancer types.

Normally, cells in your body divide and form new cells to replace worn out or dying cells, and to repair injuries. Because cancer cells continue to grow and divide, they are different from normal cells. Instead of dying, they outlive normal cells and continue to create new abnormal cells, forming a tumor. Tumors can put pressure on other organs near the ovaries.

Cancer cells can sometimes travel to other parts of the body, where they begin to grow and replace normal tissue. This process, called metastasis, occurs as the cancer cells move into the bloodstream or lymph system of the body. Cancer cells that spread from other organ sites (such as breast or colon) to the ovary are not considered ovarian cancer. Cancer type is determined by the original site of the malignancy.

What is the general outlook for women diagnosed with ovarian cancer?

In women ages 35-74, ovarian cancer is the fifth leading cause of cancer-related deaths. An estimated one woman in 75 will develop ovarian cancer during her lifetime. The American Cancer Society estimates that there will be over 22,280 new cases of ovarian cancer diagnosed this year and that more than 14,240 women will die from ovarian cancer this year.

When one is diagnosed and treated in the earliest stages, the five-year survival rate is over 90 percent. Due to ovarian cancer’s non-specific symptoms and lack of early detection tests, about 20 percent of all cases are found early, meaning in stage I or II.

If caught in stage III or higher, the survival rate can be as low as 28 percent. Due to the nature of the disease, each woman diagnosed with ovarian cancer has a different profile and it is impossible to provide a general prognosis. With almost 80% of women diagnosed in advanced stages of ovarian cancer, when prognosis is poor, we know that more needs to be done to spread awareness of this horrible disease that will take the lives of more than 14,000 women this year.

What are the Signs & Symptoms of Ovarian Cancer?

Ovarian cancer is difficult to detect, especially in the early stages. This is partly due to the fact that the ovaries – two small, almond-shaped organs on either side of the uterus – are deep within the abdominal cavity. The following are often identified by women as some of the signs and symptoms of ovarian cancer:

  • Bloating
  • Pelvic or abdominal pain
  • Trouble eating or feeling full quickly
  • Feeling the need to urinate urgently or often

Other symptoms of ovarian cancer can include:

  • Fatigue
  • Upset stomach or heartburn
  • Back pain
  • Pain during sex
  • Constipation or menstrual changes

If symptoms are new and persist for more than two weeks, it is recommended that a woman see her doctor, and a gynecologic oncologist before surgery if cancer is suspected.

Persistence of Symptoms

When the symptoms are persistent, when they do not resolve with normal interventions (like diet change, exercise, laxatives, rest) it is imperative for a woman to see her doctor. Persistence of symptoms is key. Because these signs and symptoms of ovarian cancer have been described as vague or silent, only approximately 19 percent of ovarian cancer is diagnosed in the early stages. Symptoms typically occur in advanced stages when tumor growth creates pressure on the bladder and rectum, and fluid begins to form.

Treatment Options

Surgery

Surgery to remove the cancerous growth is the most common method of diagnosis and therapy for ovarian cancer. It is best performed by a qualified gynecologic oncologist.

Most women with ovarian cancer will have surgery at some point during the course of their disease, and each surgery has different goals.

Chemotherapy

Before treatment begins, it is important to understand how chemotherapy works. Chemotherapy is the treatment of cancer using chemicals designed to destroy cancer cells or stop them from growing. The goal of chemotherapy is to cure cancer, shrink tumors prior to surgery or radiation therapy, destroy cells that might have spread, or control tumor growth.

Radiation

Radiation therapy uses high-­energy X­-rays to kill cancer cells and shrink tumors. Please note that this therapy is rarely used in the treatment of ovarian cancer in the United States. It is more often used in other parts of the body where cancer has spread.

Complementary Therapies

Some women with ovarian cancer turn toward the whole ­body approach of complementary therapy to enhance their fight against the disease, as well as to relieve stress and lessen side effects, such as fatigue, pain, and nausea.

Complementary therapies are diverse practices and products that are used along with conventional medicine. Many women have tried and benefited from the complementary therapies listed below. Speaking with other women, in addition to the healthcare team, can suggest the therapies that may be most helpful and appropriate for each woman’s lifestyle.

Clinical Trials

Clinical trials are research studies designed to find ways to improve health and cancer care. Each study tries to answer scientific questions and to find better ways to prevent, diagnose, or treat cancer. Many women undergoing treatment for ovarian cancer choose to participate in clinical trials. Through participation in these trials, patients may receive access to new therapy options that are not available to women outside the clinical trial setting.

How am I Diagnosed with Ovarian Cancer?

Most women with ovarian cancer are diagnosed with advanced-stage disease (Stage III or IV). This is because the symptoms of ovarian cancer, particularly in its early stages, often are not acute or intense, and present vaguely. In most cases, ovarian cancer is not detected during routine pelvic exams, unless the doctor notes that the ovary is enlarged. The sooner ovarian cancer is found and treated, the better a woman’s chance for survival. It is important to know that early stage symptoms can be difficult to detect, though are not always silent. As a result, it is important that women listen to their bodies and watch for early symptoms that may present.

Did You Know?

The Pap test does not detect ovarian cancer. It aids in evaluating cells for the detection of cervical cancer.

Screening Tests

Although there is no consistently-reliable screening test to detect ovarian cancer, the following tests are available and should be offered to women, especially those women at high risk for the disease:

  • Pelvic Exam: Women age 18 and older should have a mandatory annual vaginal exam. Women age 35 and older should receive an annual rectovaginal exam (physician inserts fingers in the rectum and vagina simultaneously to feel for abnormal swelling and to detect tenderness).
  • Transvaginal Sonography: This ultrasound, performed with a small instrument placed in the vagina, is appropriate, especially for women at high risk for ovarian cancer, or for those with an abnormal pelvic exam.
  • CA-125 Test: This blood test determines if the level of CA-125, a protein produced by ovarian cancer cells, has increased in the blood of a woman at high risk for ovarian cancer, or a woman with an abnormal pelvic examination.

While CA-125 is an important test, it is not always a key marker for the disease. Some non-cancerous diseases of the ovaries can also increase CA-125 levels, and some ovarian cancers may not produce enough CA-125 levels to cause a positive test. For these reasons the CA-125 test is not routinely used as a screening test for those at average risk for ovarian cancer.

Positive Tests

If any of these tests are positive, a woman should consult with a gynecologic oncologist, who may conduct a CT scan and evaluate the test results. However, the only way to more accurately confirm an ovarian cancer diagnosis is with a biopsy, a procedure in which the doctor takes a sample of the tumor and examines it under a microscope.

Research into new ovarian cancer screening tests is ongoing, and new diagnostic tests may be on the horizon. The National Ovarian Cancer Coalition monitors the latest scientific developments. Please visit their Research page for additional information.

Getting Help

To locate a physician in your area who can help with the symptoms you are suffering and aid in treatment, if necessary, please find one today using HealthLynked.com.  We are the first of its kind social ecosystem designed to connect physicians and patients for the efficient exchange of information in a secure platform designed for communication and collaboration.

Ready to get Lynked?  Go to HealthLynked.com, right now, to start getting the help you need, for free.

 

Source:

Ovarian.org

A Woman’s Story of Overcoming PCOS | 20 (plus) things you Need to Know

If you are looking for the stuff you “need to know” from the title, it’s further on down in the article.  In observance of PCOS Awareness Month, we thought we would share the true story of a young woman living with polycystic ovary syndrome (PCOS).  I know her well but interviewed her for the article anyway.  She’s my super cool middle, Delaney.

Delaney grew up a very active, wonderfully gregarious kid who moved around a few times with the Navy until we exited and settled in SoCar – that’s South Carolina, for those who don’t know.  A natural athlete, fast, nimble and taller than her peers, she quickly found herself to be a standout soccer player.  She didn’t know she couldn’t score every time she had the ball at her feet, and so she did.  Because she was quick and had incredible endurance, she also was recruited by the track coach to run the varsity 800m in seventh grade, along with a teammate who was her opposite on the field.

But soccer was her thing, and she eventually dropped the spikes to focus solely on futbol.  Running upwards of 8 miles every day in practice – anywhere from trotting to full Sprint, even backwards and sideways as an outside midfielder, she was fit in all the ways a peak performing Athlete would be.  To fuel it all, she would eat FOUR big meals every day – each bigger than those her 220 lbs weight Training father would consume.  She ate it and burned it with a ferocity on the Field we all admired.

Attack, fight, victory was her personal motto, in everything and in all ways.  Then came college.  She decided to focus on her studies and didn’t go out for the team.  In fact, just about every bit of working out came to a screeching halt.  And then, her period stopped….for a full year.

She had gained the average “freshman fifteen”, which wasn’t surprising when considering her eating habits, if anything, were filling her with added calories, and she had stopped using those calories on the field.  So, if she had always had her period as an athlete and now had even more body fat, why was she experiencing amenorrhea  (the technical term for missing your period)?   Stress?  All the life changes in general?  Purely hormonal?

Poly cystic ovarian syndrome is, at its most basic level, a hormonal imbalance, where too much of the “male” hormones are produced in a female.  While the only apparent symptom she displayed at the time was amenorrhea, her ever diligent homeopathic healer in residence, aka, her mom, was convinced she had PCOS.

First stop, her old pediatrician, who told her everything was normal; but she could go on birth control to start her period again.  After all, having one is important for so many other things in a young woman’s life, like the other hormones it generates that aid in creating increased bone density.

Not enough info, so on to an Ob/Gyn.  There, the feedback was little more along the lines of what her mom had already assumed, but they were even skeptical.  “So, let’s get an ultrasound,” my wife suggested.  The physician said you couldn’t see PCOS on an ultrasound.  As a DMS, my wife knew better.

On ultrasound, it was clear her ovaries were encased in cysts.  They were covered in follicles too numerous to count – today, 20 on an ovary will typically be used as a clear diagnosis.

Diagnosis in hand, the physician gave her the long list of troubles she was set to endure in her life – infertility, type II diabetes, a constant struggle with weight gain, hirsutism, and skin issues to name a few.  And, as if on queue, while the lack of period was the only thing she went to the physician for, she began to experience all of the negative symptoms save diabetes.

“I started to use PCOS as an excuse to eat whatever I wanted,” she says today.  “I just stopped caring about what I put in my body,” and she may have even begun to somewhat celebrate the new-found freedom from lack of discipline around diet.  Pictures of food became the standard in her social feed, and she did start to suffer the weight gain her MD predicted.  Along with that came the added pain of body image issues.

She started taking birth control to manage her cycle, and it worked.  At least, it did ensure she became regular; but deep down inside, she knew it wasn’t fixing the problem.  “I knew it was a bandaid put on to cover what was really wrong, so I quit after a year.  It wasn’t really doing anything.  It definitely was not helping fix whatever was at the root,” she said to me this Labor Day morning.

She finished college as a star student, winning all but one of the math awards given out by the University of South Carolina.  I guess I forgot to mention, she’s also brilliant, and I am very proud, of her and all of our kids.  On to New York City!

Always called to serve, Delaney decided to teach in the high schools of the Bronx.  She was not sure if it was the added stress or the increased disregard for dietary discipline, but she added even more weight with the move, though she began to workout more than before.  And, the skin issues and extra hair growth kicked in….

“I began to understand I had to do something.  Thankfully, Mom has always been a huge proponent of natural healing, so I started a few different regiments of eating more mindfully and living more intentionally,” Delaney says now.  She went through a few rounds of Whole 30, and really started to stop eating when full.  “I used to empty my plate, no matter what;… but now come home with leftovers routinely,” she says.  “If I want to have pizza, I still have pizza.  I just don’t eat a WHOLE pizza.”

The changes in diet and exercise, along with a few other healthy changes in her life, over a two-year period, have restored this vivacious young lady to the same level of health she had when she entered college in 2011.  She would say her PCOS is in remission.

“I still wonder, on occasion, about my ability to have a family; but, since my cycle is normal, naturally, I am ovulating, and my health is optimized, I think that won’t be a problem, either.”  We hope not!  We love grandkids!

Delaney would tell anyone asking her results may not be normal.  She would encourage you to seek to control PCOS in the most natural ways possible – through diet, exercise and healthy living – but she also acknowledges those methods may not be for everyone.  Definitely seek medical counsel.

So, What Is PCOS, Really?

Polycystic ovary syndrome is a hormonal condition. Hormones are substances your body makes to help make different processes happen. Some are related to your ability to have a baby, and also affect your menstrual cycle. Those that are involved in PCOS include.

  • Androgens: Often called “male” hormones, women have them, too. Those with PCOS tend to have higher levels, which can cause symptoms like hair loss, hair in places you don’t want it (such as on your face), and trouble getting pregnant.
  • Insulin: This hormone manages your blood sugar. If you have PCOS, your body might not react to insulin the way that it should.
  • Progesterone: With PCOS, your body may not have enough of this hormone. That can make you to miss your periods for a long time, or to have periods that are hard to predict.

With PCOS, your reproductive hormones are out of balance. This can lead to problems with your ovaries, such as not having your period on time, or missing it entirely.  In women who have it, it can:

  • Affect your ability to have a child (fertility)
  • Make your periods stop or become difficult to predict
  • Cause acneand unwanted hair
  • Raise your chances for other health problems, including diabetesand high blood pressure

There are treatments for the symptoms, and if you want to get pregnant, that’s still possible, though you may need to try different methods.  Many women who have PCOS don’t have cysts on their ovaries, so “polycystic” can be misleading. You might have cysts, and you might not.

What Are the Symptoms of PCOS?

If you have things such as oily skin, missed periods, or trouble losing weight, you may think those issues are just a normal part of your life. But those frustrations could actually be signs that you have polycystic ovary (or ovarian) syndrome, also known as PCOS.

The condition has many symptoms, and you may not have all of them. It’s pretty common for it to take women a while – even years – to find out they have this condition.

Things You Might Notice

You might be most bothered by some of the PCOS symptoms that other people can notice. These include:

  • Hair growth in unwanted areas. Your doctor may call this “hirsutism” (pronounced HUR-soo-tiz-uhm). You might have unwanted hair growing in places such as on your face or chin, breasts, stomach, or thumbs and toes.
  • Hair loss. Women with PCOS might see thinning hair on their head, which could worsen in middle age.
  • Weight problems. About half of women with PCOS struggle with weight gain or have a tough time losing weight.
  • Acne or oily skin. Because of hormone changes related to PCOS, you might develop pimples and oily skin. (You can have these  PCOS, of course).
  • Problems sleeping, feeling tired all the time. You could have trouble falling asleep. Or you might have a disorder known as sleep apnea. This means that even when you do sleep, you do not feel well-rested after you wake up.
  • Headaches. This is because of hormone changes with PCOS.
  • Trouble getting pregnant. PCOS is one of the leading causes of infertility.
  • Period problems. You could have irregular periods. Or you might not have a period for several months. Or you might have very heavy bleeding during your period.

How Do I Know If I Have PCOS?

There’s no single test that, by itself, shows whether you have polycystic ovary syndrome, or PCOS. Your doctor will ask you about your symptoms and give you a physical exam and blood tests to help find out if you have this condition.

PCOS is a common hormone disorder that can cause problems with your period, fertility, weight, and skin. It can also put you at risk for other conditions, such as type 2 diabetes. If you have it, the sooner you find out, the sooner you can start treatment.

What Your Doctor Will ask

Your doctor will want to know about all the signs and symptoms you’ve noticed. This is an important step to help figure out whether you have PCOS, and to rule out other conditions that cause similar symptoms.

You’ll need to answer questions about your family’s medical history, including whether your mother or sister has PCOS or problems getting pregnant. This information is helpful — PCOS tends to run in families.

Be ready to discuss any period problems you’ve had, weight changes, and other concerns.

Your doctor may diagnose PCOS if you have at least two of these symptoms:

  • Irregular periods
  • Higher levels of androgen (male hormones) shown in blood tests or through symptoms like acne, male-pattern balding, or extra hair growth on your face, chin, or body
  • Cysts in your ovaries as shown in an ultrasound exam

What’s the Treatment for PCOS?

Treatments can help you manage the symptoms of polycystic ovary syndrome (PCOS) and lower your odds for long-term health problems such as diabetes and heart disease.

You and your doctor should talk about what your goals are, then you can come up with a treatment plan. For example, if you want to get pregnant and are having trouble, then your treatment would focus on helping you conceive. If you want to tame PCOS-related acne, your treatment would be geared toward skin problems.

Healthy Habits

  • One of the best ways to deal with PCOSis to eat well and exercise
  • Many women with PCOS are overweightor obese. Losing just 5% to 10% of your body weight may ease some symptoms and help make your periods more regular. It may also help manage problems with blood sugar levels and ovulation.
  • Since PCOS could lead to high blood sugar, your doctor may want you to limit starchy or sugary foods. Instead, eat foods and meals that have plenty of fiber, which raise your blood sugarlevel slowly.
  • Staying active helps you control your blood sugar and insulin, too. And exercisingevery day will help you with your weight.
  • Staying active helps you control your blood sugar and insulin, too. And exercisingevery day will help you with your weight.

Hormone Treatments and Medication

Birth control is the most common PCOS treatment for women who don’t want to get pregnant. Hormonal birth control — pills, a skin patch, vaginal ring, shots, or a hormonal IUD (intrauterine device) — can help restore regular periods. The hormones also treat acne and unwanted hair growth.

These birth control methods may also lower your chance of having endometrial cancer, in the inner lining of the uterus.

Taking just a hormone called progestin could help get your periods back on track. It doesn’t prevent pregnancies or treat unwanted hair growth and acne. But it can lower the chance of uterine cancer.

Metformin (Fortamet, Glucophage) lowers insulin levels. It can help with weight loss and may prevent you from getting type 2 diabetes. It may also make you more fertile.

If birth control doesn’t stop hair growth after 6 months, your doctor may prescribe spironolactone (Aldactone). It lowers the level of a type of sex hormone called androgens. But you shouldn’t take it if you’re pregnant or plan to become pregnant, because it can cause birth defects.

Weight Loss

When a healthy diet and regular exercise aren’t enough, medications can make losing weight easier. Different drugs work in different ways. For example, orlistat (Alli, Xenical) stops your body from digesting some of the fat in your food, so it may also improve your cholesterol levels. Lorcaserin (Belviq) makes you feel less hungry. Your doctor will prescribe the medication they think will be the most successful for you.

Weight loss surgery could help if you’re severely obese and other methods haven’t worked. The change in your weight afterward can regulate your menstrual cycle and hormones and cut your odds of having diabetes.

Hair Removal

Products called depilatories, including creams, gels, and lotions, break down the protein structure of hair so it falls out of the skin. Follow the directions on the package.

A process like electrolysis (a way to remove individual hairs by using an electric current to destroy the root) or laser therapy destroys hair follicles. You’ll need several sessions, and though some hair may come back, it should be finer and less noticeable.

Fertility

Your doctor may prescribe medication to help you get pregnant. Clomiphene and letrozole encourage steps in the process that trigger ovulation. If they don’t work, you can try shots of hormones called gonadotropins.

A surgery called ovarian drilling might make your ovaries work better when ovulation medications don’t, but it’s being done less often than it used to. The doctor makes a small cut in your belly and uses a tool called a laparoscope with a needle to poke your ovary and wreck a small part of it. The procedure changes your hormone levels and may make it easier for you to ovulate.

With in vitro fertilization, or IVF, your egg is fertilized outside of your body and then placed back inside your uterus. This may be the best way to get pregnant when you have PCOS, but it can be expensive.

What Are the Complications of PCOS?

If you have polycystic ovary syndrome, your ovaries may contain many tiny cysts that cause your body to produce too many hormones called androgens.

In men, androgens are made in the testes. They’re involved in the development of male sex organs and other male characteristics, like body hair. In women, androgens are made in the ovaries, but are later turned into estrogens. These are hormones that play a vital role in the reproductive system, as well as the health of your heart, arteries, skin, hair, brain, and other body parts and systems.

If you have PCOS and your androgen levels are too high, you have higher odds for a number of possible complications. (These may differ from woman to woman):

Trouble Getting Pregnant

  • Cysts in the ovaries can interfere with ovulation. That’s when one of your ovaries releases an egg each month. If a healthy egg isn’t available to be fertilized by a sperm, you can’t get pregnant.
  • You may still be able to get pregnant if you have PCOS. But you might have to take medicine and work with a fertility specialist to make it happen.

Insulin Issues

Doctors aren’t sure what causes PCOS. One theory is that insulin resistance may cause your body to make too many androgens.

Insulin is a hormone that helps the cells in your body absorb sugar (glucose) from your blood to be used as energy later. If you have insulin resistance, the cells in your muscles, organs, and other tissue don’t absorb blood sugar very well. As a result, you can have too much sugar moving through your bloodstream. This is called diabetes, and it can cause problems with your cardiovascular and nervous systems.

Other Possible Problems

You might have metabolic syndrome. This is a group of symptoms that raise the risk of cardiovascular disease, such as high triglyceride and low HDL (“good”) cholesterol levels, high blood pressure, and high blood sugar levels.  Other common complications of PCOS include:

  • Depression
  • Anxiety
  • Bleeding from the uterus and higher risk of uterine cancer
  • Sleep problems
  • Inflammation of the liver

Some complications of PCOS may not be serious threats to your health, but they can be unwanted and embarrassing:

  • Abnormal body or facial hair growth
  • Thinning hair on your head
  • Weight gain around your middle
  • Acne, dark patches, and other skin problems

Most women at some point have to contend with weight, but for women with polycystic ovary syndrome(PCOS), losing weight can become a constant struggle.

PCOS is the most common hormonal disorder in women of childbearing age and can lead to issues with fertility. Women who have PCOS have higher levels of male hormones and are also less sensitive to insulin or are “insulin-resistant.” Many are overweight or obese. As a result, these women can be at a higher risk of diabetes, heart disease, sleep apnea, and uterine cancer.

If you have PCOS, certain lifestyle changes can help you shed pounds and reduce the disease’s severity.

Why does polycystic ovary syndrome cause weight gain?

PCOS makes it more difficult for the body to use the hormone insulin, which normally helps convert sugars and starches from foods into energy. This condition — called insulin resistance– can cause insulin and sugar — glucose — to build up in the bloodstream.

High insulin levels increase the production of male hormones called androgens. High androgen levels lead to symptoms such as body hair growth, acne, irregular periods — and weight gain. Because the weight gain is triggered by male hormones, it is typically in the abdomen. That is where men tend to carry weight. So, instead of having a pear shape, women with PCOS have more of an apple shape.

Abdominal fat is the most dangerous kind of fat. That’s because it is associated with an increased risk of heart disease and other health conditions.

What are the risks associated with PCOS-related weight gain?

No matter what the cause, weight gain can be detrimental to your health. Women with PCOS are more likely to develop many of the problems associated with weight gain and insulin resistance, including:

  • Type 2 diabetes
  • High cholesterol
  • High blood pressure
  • Sleep apnea
  • Infertility
  • Endometrial cancer

Many of these conditions can lead to heart disease. In fact, women with PCOS are four to seven times more likely to have a heart attack than women of the same age without the condition.

Experts think weight gain also helps trigger PCOS symptoms, such as menstrual abnormalities and acne.

What can I do to lose weight if I have polycystic ovary syndrome?

Losing weight not only cuts your risk for many diseases, it can also make you feel better. When you have PCOS, shedding just 10% of your body weight can bring your periods back to normal. It can also help relieve some of the symptoms of polycystic ovary syndrome.

Weight loss can improve insulin sensitivity. That will reduce your risk of diabetes, heart disease, and other PCOS complications.

To lose weight, start with a visit to your doctor. The doctor will weigh you and check your waist size and body mass index. Body mass index is also called BMI, and it is the ratio of your height to your weight.

Your doctor may also prescribe medication. Several medications are approved for PCOS, including birth control pills and anti-androgen medications. The anti-androgen medications block the effects of male hormones. A few medications are used specifically to promote weight loss in women with PCOS. These include:

  • Metformin (Glucophage). Metformin is a diabetes drug that helps the body use insulin more efficiently. It also reduces testosterone production. Some research has found that it can help obese women with PCOS lose weight.
  • Thiazolidinediones. These should be used with contraception. The drugs pioglitazone (Actos) and rosiglitazone (Avandia) also help the body use insulin. In studies, these drugs improved insulin resistance. But their effect on body weight is unclear. All patients using Avandia must review and fully understand the cardiovascular risks. Research has found that Flutamide (Eulexin), an anti-androgen drug, helps obese women with PCOS lose weight. It also improves their blood sugar levels. The drug can be given alone or with metformin.

In addition to taking medication, adding healthy habits into your lifestyle can help you keep your weight under control:

  • Eat a high-fiber, low-sugar diet. Load up on fruits, vegetables, and whole grains. Avoid processed and fatty foods to keep your blood sugar levels in check. If you’re having trouble eating healthy on your own, talk to your doctor or a dietitian.
  • Eat four to six small meals throughout the day, rather than three large meals. This will help control your blood sugar levels.
  • Exercise for at least 30 minutes a day on most, if not all, days of the week.
  • Work with your doctor to track your cholesterol and blood pressure levels.
  • If you smoke, get involved in a program that can help you quit.

PCOS and Your Fertility — and What You Can Do About It

One of the most common reasons a woman has trouble getting pregnant is a condition called polycystic ovary syndrome (PCOS).  It’s a hormone problem that interferes with the reproductive system.   When you have PCOS, your ovaries are larger than normal. These bigger ovaries can have many tiny cysts that contain immature eggs.

Hormone Differences

PCOS causes a woman’s body to produce higher-than-normal levels of androgens. These are hormones that are usually thought of as male hormones, because men have much higher levels of androgens than women.

Androgens are important in the development of male sex organs and other male traits.  In women, androgens are usually converted into the hormone estrogen.

Ovulation Problems

Elevated levels of androgens interfere with the development of your eggs and the regular release of your eggs. This process is called ovulation.

If a healthy egg isn’t released, it can’t be fertilized by sperm, meaning you can’t get pregnant. PCOS can cause you to miss your menstrual period or have irregular periods. This can be one of the first signs that you may have a problem such as PCOS.

Regulating Your Period

Fortunately, there are some treatments that can help women with PCOS have healthy pregnancies.

Your doctor may prescribe birth control pills that contain man-made versions of the hormones estrogen and progestin. These pills can help regulate your menstrual cycle by reducing androgen production.

If you cannot tolerate a combination birth control pill, your doctor might recommend a progestin-only pill.

You take this pill for about 2 weeks a month, for about 1-2 months. It’s also designed to help regulate your period.

Medicines to Help You Ovulate

You won’t be able to get pregnant while you’re taking birth control pills for PCOS. But if you need help ovulating so that you can become pregnant, certain medicines may help:

  • Clomiphene is an anti-estrogen drug that you take at the beginning of your cycle.
  • If clomiphene doesn’t help with ovulation, you may be prescribed the diabetes drug metformin.
  • If clomiphene and metformin don’t work, your doctor may prescribe a medication containing a follicle-stimulating hormone (FSH) and a luteinizing hormone (LH). You get this medicine in a shot.
  • One other drug that helps with ovulation is letrozole. It’s sometimes used when other medications aren’t effective.

If you have PCOS and you want to get pregnant, you should work with a doctor who is a specialist in reproductive medicine. This type of doctor is also known as a fertility specialist.

A specialist will help make sure you get the right dose of medicines, help with any problems you have, and schedule regular checkups and ultrasounds to see how you’re doing. (An ultrasound is a machine that uses sound waves to create images of the inside of your body. It’s a painless procedure that can track the growth and development of your baby).

Lifestyle Changes

For some women, gaining a lot of weight can affect their hormones. In turn, losing weight, if you’re obese or overweight, may help get your hormones back to normal levels. Losing 10% of your body weight may help your menstrual cycle become more predictable. This should help you get pregnant.

In general, living a healthier lifestyle with a better diet, regular exercise, no smoking, less stress, and control of diabetes and other medical conditions should improve your fertility odds.

Remember, if your period isn’t happening when it should, or you’ve already been diagnosed with PCOS, work closely with your doctor to help get it under control. And if you want to get pregnant, talk with a fertility specialist.

Getting Help  

If you’re having irregular periods or are unable to get pregnant, see your doctor. The same holds for:

  • Mood changes
  • Unexplained weight gain
  • Changes in your hair or skin

These symptoms may might not be caused by PCOS but could signal other serious health issues.

If anything is this article sounds like something you are dealing with, get connected with a doctor in your area who can help.  Using HealthLynked, you can find a physician and securely share relevant health information with them, collaborating more closely on your healthcare than ever before possible.

Ready to get Lynked?  Sign up today for Free at HealthLynked.com!

Adapted from – WebMd

The Benefits of Breastfeeding for Both Mother and Baby | WebMD


In honor of Breastfeeding Awareness Month, we will be sharing a series of articles promoting breastfeeding.  This next one is about the “ABC’s” of breastfeeding – a brief overview of the basics you should know, republished in full from WebMD.


Breastfeeding Overview

Making the decision to breastfeed is a personal matter. It’s also one that’s likely to draw strong opinions from friends and family.

Many medical experts, including the American Academy of Pediatrics (AAP) and the American College of Obstetricians and Gynecologists, strongly recommend breastfeeding exclusively (no formula, juice, or water) for 6 months. And breastfeeding for a year at least with other foods which should be started at 6 months of age, such as vegetables, grains, fruits, proteins.

But you and your baby are unique, and the decision is up to you. This overview of breastfeeding can help you decide.

What Are the Benefits of Breastfeeding for Your Baby?

Breast milk provides the ideal nutrition for infants. It has a nearly perfect mix of vitamins, protein, and fat — everything your baby needs to grow. And it’s all provided in a form more easily digested than infant formula. Breast milk contains antibodies that help your baby fight off viruses and bacteria. Breastfeeding lowers your baby’s risk of having asthma or allergies. Plus, babies who are breastfed exclusively for the first 6 months, without any formula, have fewer ear infections, respiratory illnesses, and bouts of diarrhea. They also have fewer hospitalizations and trips to the doctor.

Breastfeeding has been linked to higher IQ scores in later childhood in some studies. What’s more, the physical closeness, skin-to-skin touching, and eye contact all help your baby bond with you and feel secure. Breastfed infants are more likely to gain the right amount of weight as they grow rather than become overweight children. The AAP says breastfeeding also plays a role in the prevention of SIDS (sudden infant death syndrome). It’s been thought to lower the risk of diabetes, obesity, and certain cancers as well, but more research is needed.

Are There Breastfeeding Benefits for the Mother?

Breastfeeding burns extra calories, so it can help you lose pregnancy weight faster. It releases the hormone oxytocin, which helps your uterus return to its pre-pregnancy size and may reduce uterine bleeding after birth. Breastfeeding also lowers your risk of breast and ovarian cancer. It may lower your risk of osteoporosis, too.

Since you don’t have to buy and measure formula, sterilize nipples, or warm bottles, it saves you time and money. It also gives you regular time to relax quietly with your newborn as you bond.

Will I Make Enough Milk to Breastfeed?

The first few days after birth, your breasts make an ideal “first milk.” It’s called colostrum. Colostrum is thick, yellowish, and scant, but there’s plenty to meet your baby’s nutritional needs. Colostrum helps a newborn’s digestive tract develop and prepare itself to digest breast milk.

Most babies lose a small amount of weight in the first 3 to 5 days after birth. This is unrelated to breastfeeding.

As your baby needs more milk and nurses more, your breasts respond by making more milk. Experts recommend breastfeeding exclusively (no formula, juice, or water) for 6 months. If you supplement with formula, your breasts might make less milk.

Even if you breastfeed less than the recommended 6 months, it’s better to breastfeed for a short time than no time at all. You can add solid food at 6 months but also continue to breastfeed if you want to keep producing milk.

What’s the Best Position for Breastfeeding?

The best position for you is the one where you and your baby are both comfortable and relaxed, and you don’t have to strain to hold the position or keep nursing. Here are some common positions for breastfeeding your baby:

  • Cradle position. Rest the side of your baby’s head in the crook of your elbow with his whole body facing you. Position your baby’s belly against your body so he feels fully supported. Your other, “free” arm can wrap around to support your baby’s head and neck — or reach through your baby’s legs to support the lower back.
  • Football position. Line your baby’s back along your forearm to hold your baby like a football, supporting his head and neck in your palm. This works best with newborns and small babies. It’s also a good position if you’re recovering from a cesarean birth and need to protect your belly from the pressure or weight of your baby.
  • Side-lying position. This position is great for night feedings in bed. Side-lying also works well if you’re recovering from an episiotomy, an incision to widen the vaginal opening during delivery. Use pillows under your head to get comfortable. Then snuggle close to your baby and use your free hand to lift your breast and nipple into your baby’s mouth. Once your baby is correctly “latched on,” support your baby’s head and neck with your free hand so there’s no twisting or straining to keep nursing.

How Do I Get My Baby to ‘Latch on’ During Breastfeeding?

Position your baby facing you, so your baby is comfortable and doesn’t have to twist his neck to feed. With one hand, cup your breast and gently stroke your baby’s lower lip with your nipple. Your baby’s instinctive reflex will be to open the mouth wide. With your hand supporting your baby’s neck, bring your baby’s mouth closer around your nipple, trying to center your nipple in the baby’s mouth above the tongue.

You’ll know your baby is “latched on” correctly when both lips are pursed outward around your nipple. Your infant should have all of your nipple and most of the areola, which is the darker skin around your nipple, in his mouth. While you may feel a slight tingling or tugging, breastfeeding should not be painful. If your baby isn’t latched on correctly and nursing with a smooth, comfortable rhythm, gently nudge your pinky between your baby’s gums to break the suction, remove your nipple, and try again. Good “latching on” helps prevent sore nipples.

What Are the ABCs of Breastfeeding?

  • A = Awareness. Watch for your baby’s signs of hunger, and breastfeed whenever your baby is hungry. This is called “on demand” feeding. The first few weeks, you may be nursing eight to 12 times every 24 hours. Hungry infants move their hands toward their mouths, make sucking noises or mouth movements, or move toward your breast. Don’t wait for your baby to cry. That’s a sign he’s too hungry.
  • B = Be patient. Breastfeed as long as your baby wants to nurse each time. Don’t hurry your infant through feedings. Infants typically breastfeed for 10 to 20 minutes on each breast.
  • C = Comfort. This is key. Relax while breastfeeding, and your milk is more likely to “let down” and flow. Get yourself comfortable with pillows as needed to support your arms, head, and neck, and a footrest to support your feet and legs before you begin to breastfeed.

Are There Medical Considerations With Breastfeeding?

In a few situations, breastfeeding could cause a baby harm. You should not breastfeed if:

  • You are HIV positive. You can pass the HIV virus to your infant through breast milk.
  • You have active, untreated tuberculosis.
  • You’re receiving chemotherapy for cancer.
  • You’re using an illegal drug, such as cocaine or marijuana.
  • Your baby has a rare condition called galactosemia and cannot tolerate the natural sugar, called galactose, in breast milk.
  • You’re taking certain prescription medications, such as some drugs for migraine headaches, Parkinson’s disease, or arthritis.

Talk with your doctor before starting to breastfeed if you’re taking prescription drugsof any kind. Your doctor can help you make an informed decision based on your particular medication.

Having a cold or flu should not prevent you from breastfeeding. Breast milk won’t give your baby the illness and may even give antibodies to your baby to help fight off the illness.

Also, the AAP suggests that — starting at 4 months of age — exclusively breastfed infants, and infants who are partially breastfed and receive more than one-half of their daily feedings as human milk, should be supplemented with oral iron. This should continue until foods with iron, such as iron-fortified cereals, are introduced in the diet. The AAP recommends checking iron levels in all children at age 1.

Discuss supplementation of both iron and vitamin D with your pediatrician Your doctor can guide you on recommendations about the proper amounts for both your baby and you, when to start, and how often the supplements should be taken.

Why Do Some Women Choose Not to Breastfeed?

  • Some women don’t want to breastfeed in public.
  • Some prefer the flexibility of knowing that a father or any caregiver can bottle-feed the baby any time.
  • Babies tend to digest formula more slowly than breast milk, so bottle feedings may not be as frequent as breastfeeding sessions.

The time commitment, and being “on-call” for feedings every few hours of a newborn’s life, isn’t feasible for every woman. Some women fear that breastfeeding will ruin the appearance of their breasts. But most breast surgeons would argue that age, gravity, genetics, and lifestyle factors like smoking all change the shape of a woman’s breasts more than breastfeeding does.

What Are Some Common Challenges With Breastfeeding?

  • Sore nipples. You can expect some soreness in the first weeks of breastfeeding. Make sure your baby latches on correctly, and use one finger to break the suction of your baby’s mouth after each feeding. That will help prevent sore nipples. If you still get sore, be sure you nurse with each breast fully enough to empty the milk ducts. If you don’t, your breasts can become engorged, swollen, and painful. Holding ice or a bag of frozen peas against sore nipples can temporarily ease discomfort. Keeping your nipples dry and letting them “air dry” between feedings helps, too. Your baby tends to suck more actively at the start. So begin feedings with the less-sore nipple.
  • Dry, cracked nipples. Avoid soaps, perfumed creams, or lotions with alcohol in them, which can make nipples even more dry and cracked. You can gently apply pure lanolin to your nipples after a feeding, but be sure you gently wash the lanolin off before breastfeeding again. Changing your bra pads often will help your nipples stay dry. And you should use only cotton bra pads.
  • Worries about producing enough milk.A general rule of thumb is that a baby who’s wetting six to eight diapers a day is most likely getting enough milk. Avoid supplementing your breast milk with formula, and never give your infant plain water. Your body needs the frequent, regular demand of your baby’s nursing to keep producing milk. Some women mistakenly think they can’t breastfeed if they have small breasts. But small-breasted women can make milk just as well as large-breasted women. Good nutrition, plenty of rest, and staying well hydrated all help, too.
  • Pumping and storing milk. You can get breast milk by hand or pump it with a breast pump. It may take a few days or weeks for your baby to get used to breast milk in a bottle. So begin practicing early if you’re going back to work. Breast milk can be safely used within 2 days if it’s stored in a refrigerator. You can freeze breast milk for up to 6 months. Don’t warm up or thaw frozen breast milk in a microwave. That will destroy some of its immune-boosting qualities, and

it can cause fatty portions of the breast milk to become super hot. Thaw breast milk in the refrigerator or in a bowl of warm water instead.

  • Inverted nipples. An inverted nipple doesn’t poke forward when you pinch the areola, the dark skin around the nipple. A lactation consultant — a specialist in breastfeeding education — can give simple tips that have allowed women with inverted nipples to breastfeed successfully.
  • Breast engorgement. Breast fullness is natural and healthy. It happens as your breasts become full of milk, staying soft and pliable. But breast engorgement means the blood vessels in your breast have become congested. This traps fluid in your breasts and makes them feel hard, painful, and swollen. Alternate heat and cold, for instance using ice packs and hot showers, to relieve mild symptoms. It can also help to release your milk by hand or use a breast pump.
  • Blocked ducts. A single sore spot on your breast, which may be red and hot, can signal a plugged milk duct. This can often be relieved by warm compresses and gentle massage over the area to release the blockage. More frequent nursing can also help.
  • Breast infection (mastitis). This occasionally results when bacteria enter the breast, often through a cracked nipple after breastfeeding. If you have a sore area on your breast along with flu-like symptoms, fever, and fatigue, call your doctor. Antibiotics are usually needed to clear up a breast infection, but you can most likely continue to breastfeed while you have the infection and take antibiotics. To relieve breast tenderness, apply moist heat to the sore area four times a day for 15 to 20 minutes each time.
  • Stress. Being overly anxious or stressed can interfere with your let-down reflex. That’s your body’s natural release of milk into the milk ducts. It’s triggered by hormones released when your baby nurses. It can also be triggered just by hearing your baby cry or thinking about your baby. Stay as relaxed and calm as possible before and during nursing — it can help your milk let down and flow more easily. That, in turn, can help calm and relax your infant.
  • Premature babies may not be able to breastfeed right away. In some cases, mothers can release breast milk and feed it through a bottle or feeding tube.
  • Warning signs. Breastfeeding is a natural, healthy process. But call your doctor if:
  • Your breasts become unusually red, swollen, hard, or sore.
  • You have unusual discharge or bleeding from your nipples.
  • You’re concerned your baby isn’t gaining weight or getting enough milk.

Where Can I Get Help With Breastfeeding?

Images of mothers breastfeeding their babies make it look simple — but most women need some help and coaching. It can come from a nurse, doctor, family member, or friend, and it helps mothers get over possible bumps in the road.

Reach out to friends, family, and your doctor with any questions you may have. Most likely, the women in your life have had those same questions.

SOURCE: WebMD Medical Reference Reviewed by Dan Brennan, MD on December 5, 2017

Sources

 

SOURCES:

News release, American Academy of Pediatrics.

Baker, R. Pediatrics, November 2010.

American Academy of Pediatrics: “Policy Statement: Breastfeeding and the Use of Human Milk.”

American College of Obstetricians and Gynecologists: “Breastfeeding Your Baby.”

CDC: “Proper Handling and Storage of Human Milk.”

National Women’s Health Information Center: “Benefits of Breastfeeding.”

National Women’s Health Information Center: “Questions and Answers About Breastfeeding.”

National Women’s Health Information Center: “How Lifestyle Affects Breast Milk.”

La Leche League International: “How Do I Position My Baby to Breastfeed?”

American Academy of Family Physicians: “Breastfeeding: Hints To Help You Get Off to a Good Start.”

National Library of Medicine: “Overcoming Breastfeeding Problems.”

KidsHealth.org: “Feeding Your Newborn.”

American College of Nurse-Midwives, GotMom.org: “Breastfeeding with Confidence.”

© 2017 WebMD, LLC. All rights reserved.