“There are no words to express just how grateful I am for this gift,” says Andy Sandness, the recipient of Mayo Clinic’s first-ever face transplant. This video profiles Mr. Sandness’ decade long journey – from a “devastating” injury to being selected as Mayo’s first patient to undergo this life-transforming procedure.
Dr. Tobias Kohler, a urologist at Mayo Clinic, explains a promising new treatment for benign prostatic hyperplasia, or BPH. This interview originally aired on Feb. 24, 2018.
Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a study published today in the New England Journal of Medicine.
“We observed that Imetelstat was active and induced morphologic and molecular remissions in some patients with myelofibrosis,” says Ayalew Tefferi, M.D., a hematologist at Mayo Clinic and lead author of the study. “We also observed that Imtelstat demonstrated selective anti-clonal activity, inhibiting the growth of cancer cells, which we had not previously documented with other drugs.”
Myelofibrosis is a chronic myeloid cancer in which bone marrow cells that produce blood cells develop and function abnormally. The result is the formation of scar tissue in the bone marrow (fibrosis), severe anemia that often requires transfusion, weakness, fatigue, and an enlarged spleen and liver. Patients with myelofibrosis harbor one of several genetic mutations in their blood stem cells, including JAK2, MPL, CALR, ASXL1 and spliceosome pathway mutations.3317325_0009”Typically, myelofibrosis is characterized by marrow scarring, and, although patients may derive symptomatic relief from other treatments, such as ruxolitinib, they usually do not revert back to normal bone marrow,” Dr. Tefferi says. “Some patients treated with Imetelstat have reverted back to normal bone marrow.” Imetelstat works by inhibiting telomerase activity in tumor cells, which leads to cell death.
Mayo Clinic patient’s first impressions with bionic eye
It took the 911 dispatcher a moment to realize the brother and sister injured in the accident were not in the same car … they had crashed into each other. One was leaving the farm and the other was coming home. Their mom says their survival was nothing short of a miracle.
Jay Smith, M.D., vice chair of Physical Medicine and Rehabilitation at Mayo Clinic describes a clinical trial to evaluate the safety and efficacy of adipose-derived mesenchymal stromal cell injections as a treatment for patients with osteoarthritic knees.
In the three years leading up to Mayo Clinic’s first face transplant procedure, dozens of medical specialists rehearsed the full transplant operation more than 30 times. Here is a detailed look at how they achieved a remarkable transformation with a very complex surgery.
Mayo Clinic’s Robert Orenstein, D.O., and John K. DiBaise, M.D., explain and demonstrate the FMT procedures and techniques.
To request an appointment, visit http://www.mayoclinic.org/diseases-conditions/c-difficile/diagnosis-treatment/request-appointment/ptc-20202448?mc_id=us&utm_source=youtube&utm_medium=sm&utm_content=video&utm_campaign=mayoclinic&geo=national&placementsite=enterprise&cauid=100504
Researchers at Mayo Clinic have found that a mild to moderate reduction in calories effectively prevents and reverses polycystic kidney disease (PKD) in mice. The results appear online today in the Journal of the American Society of Nephrology.
“Currently, there is no FDA-approved treatment, and the only thing that can be done is dialysis or renal transplantation,” explains Eduardo Chini, M.D., Ph.D., anesthesiologist and researcher for Mayo Clinic’s Robert and Arlene Kogod Center on Aging and lead author of the study. “We have found that a very simple measure, like decreasing the amount of calories that are taken in, even by only 10 percent, can very significantly decrease the burden of this disease.”
Mayo Clinic’s Christopher Sletten, Ph.D., ABPP discussing Central Sensitization Syndrome, which is the prevailing theory of the cause of chronic pain & other chronic symptoms. A patient and/or provider understanding of this process can lead to seeking appropriate treatments including the Pain Rehab Center (PRC) at Mayo Clinic’s Florida campus.
Learn more about the PRC program in Florida: http://mayocl.in/prcfl