Liquid Biopsy Promotes Precision Medicine By Tracking Patient’s Cancer

In a study published in Nature Communications, Dr. Muhammed Murtaza, who holds a joint appointment at Mayo Clinic and Translational Genomics Research Institute (TGEN), and colleagues, describe an extensive comparison between biopsy results and analysis of ctDNA in a patient with breast cancer.

In the following video, Dr. Murtaza describes how circulating tumor DNA in blood could inform physicians on best treatments for individual patients.

For more information, visit:
►Mayo Clinic Center for Individualized Medicine: http://mayoresearch.mayo.edu/center-for-individualized-medicine/?mc_id=us&utm_source=youtube&utm_medium=sm&utm_content=video&utm_campaign=mayoclinic&geo=national&placementsite=enterprise&cauid=100504
►TGEN: https://tgen.org/home/news/2015-media-releases/tgen-shows-liquid-biopsies-could-help-cancer-patients.aspx#.VjooyWdRGUl

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Differentiating Childhood Apraxia of Speech (CAS) from other types of speech sound disorders

Dr. Edythe Strand, Emeritus Professor and Consultant, division of Speech Pathology, Department of Neurology, Mayo Clinic, compares and contrasts CAS with other types of speech disorders, including phonological impairment and dysarthria.

For more information, visit http://mayocl.in/2ifnYX3

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MR Fusion Biopsy at Mayo Clinic

MR fusion-guided biopsy of the prostate is a state of the art technique for the early diagnosis of prostate cancer. It allows for diagnosis of difficult to reach cancers with conventional biopsy techniques. Uses the most advanced technology to image the prostate with MRI.

Learn more about this new technique with Mayo Clinic urologist Julio Gundian.

More information at www.mayoclinic.org

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Speech Disorder Called Apraxia can Progress to Neurodegenerative Disease: Dr Joseph Duffy



It may start with a simple word you can’t pronounce. Your tongue and lips stumble, and gibberish comes out.

Misspeaking might draw a chuckle from family and friends. But, then, it keeps happening. Progressively, more and more speech is lost. Some patients eventually become mute from primary progressive apraxia of speech, a disorder related to degenerative neurologic disease.

Two Mayo Clinic researchers have spent more than a decade uncovering clues to apraxia of speech. Keith Josephs, M.D., a neurologist, and Joseph R. Duffy, Ph.D., a speech pathologist, will present “My Words Come Out Wrong: When Thought and Language Are Disconnected from Speech” on Sunday, Feb. 14, at the American Association for the Advancement of Science annual meeting in Washington, D.C.

In this video Dr. Duffy discusses the disorder.

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Treatment of Childhood Apraxia of Speech (CAS)



Dr. Edythe Strand, Emeritus Professor and Consultant, division of Speech Pathology, Department of Neurology, Mayo Clinic, discusses basic approaches to treatment of CAS, providing a number of video examples of therapy.

For more information, visit http://mayocl.in/2ifnYX3

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Dietitian’s Tips on Following a Low Fiber Diet – Mayo Clinic

Mayo Clinic’s Melissa Stewart, RD (Registered Dietitian) talks about a low fiber diet for lower gastrointestinal disorders.

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Diagnosis of Childhood Apraxia of Speech (CAS)

Dr. Edythe Strand, Emeritus Professor and Consultant, division of Speech Pathology, Department of Neurology, Mayo Clinic, explains why children with CAS often have co-existing language and speech disorders. She discusses when and who should diagnosis CAS.

For more information, visit: http://www.mayoclinic.org/diseases-conditions/childhood-apraxia-of-speech/basics/definition/con-20031147?mc_id=us&utm_source=youtube&utm_medium=sm&utm_content=video&utm_campaign=mayoclinic&geo=national&placementsite=enterprise&cauid=100504

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Big Steps for Amarachi

To run, play tag, and try the sport of basketball; those are the new activities a girl from Nigeria is looking forward to most, after a life-changing trip to Mayo Clinic.

“She is very happy, and we are too quite frankly,” says pediatric orthopedic surgeon Todd Milbrandt, M.D. “She’s just a phenomenal young woman and a really motivated patient in this situation,” added orthopedic surgeon S. Andrew Sems, M.D.

Step-by-step, doctors were able to restore her legs to normal, so that she might enjoy the simple steps that most of us take for granted. Here’s Dennis Douda for the Mayo Clinic News Network.

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M.D. – Ph.D. PROGRAM AT MAYO CLINIC

Take a look at the daily life of M.D. – Ph.D. Student Lucas Carlstrom as he learns to translate knowledge from bench to bedside on the way to becoming a physician scientist in the joint Mayo Medical School and Mayo Graduate School Medical Scientist Training Program.

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Researchers Extend Lifespan by as Much as 35 Percent in Mice

Researchers at Mayo Clinic have shown that senescent cells – cells that no longer divide and accumulate with age – negatively impact health and shorten lifespan by as much as 35 percent in normal mice. The results, which appear today in Nature, demonstrate that clearance of senescent cells delays tumor formation, preserves tissue and organ function, and extends lifespan without observed adverse effects.

“Cellular senescence is a biological mechanism that functions as an ‘emergency brake’ used by damaged cells to stop dividing,” says Jan van Deursen, Ph.D., Chair of Biochemistry and Molecular biology at Mayo Clinic, and senior author of the paper. “While halting cell division of these cells is important for cancer prevention, it has been theorized that once the ‘emergency brake’ has been pulled, these cells are no longer necessary.”

The immune system sweeps out the senescent cells on a regular basis, but over time becomes less effective. Senescent cells produce factors that damage adjacent cells and cause chronic inflammation, which is closely associated with frailty and age-related diseases.

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Mayo Clinic SURF program: Tamiel Turley’s Story

Meet Tamiel Turley, a senior at Texas Woman’s University who spent 10 weeks away from her family this past summer as a participant in the prestigious Mayo Clinic Summer Undergraduate Research Fellowship (SURF).

Developed by Mayo Graduate School, Mayo’s school for Ph.D. training, SURF is the first-of-its-kind initiative in the nation to bring together diverse college students from across the country for summer research apprenticeship training with Mayo Clinic scientists.

Learn more about Tamiel’s experience with the program, which exists on all Mayo campuses and receives nearly 1,200 applicants per year.

Learn more about SURF by visiting www.mayo.edu.

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